Because stimulating the G-spot puts indirect pressure on the bladder, some women feel like they want to urinate when it’s touched. Women are encouraged to relax and work past these sensations. In time, the Skene’s gland will release a clear liquid containing glucose and prostatic acid into the urethral canal. Its chemical composition is similar to semen. In Tantric literature, this liquid is revered and known as amrita, which means nectar of the goddess.
In 2002, Italian academic Emanuele Jannini showed that Skene's glands vary significantly in size, and in some cases may be absent entirely. If indeed Skene's glands cause female ejaculation and G-spot orgasms, these differences may explain why some women never experience this kind of climax.