Anal intercourse is considered a high risk practice, and the World Health Organization (WHO) suggests that safe sex practices, including the use of lubrication, should be followed during anal sex.
Example of an anal lubricant.
Pictured: Wicked Jelle.
While most manufactured sex lubricants can be used for anal sex, some lubricants are specifically crafted and marketed for anal use. They may be thicker, plushier, longer-lasting, or provide other desired traits that would aid in anal penetration.